healthSpring

Pharmacokinetics and human health

Human health computing — PK/PD, gut microbiome, biosignal, endocrinology, comparative medicine, drug discovery. Sovereign NLME replaces proprietary NONMEM/Monolix.

51,655lines of Rust
989test functions
286files
97crates

syntheticChemistry/healthSpring

Capabilities

CategoryPrimitives
PK/PDHill, PBPK, population Monte Carlo, Michaelis-Menten, species-agnostic dosing
MicrobiomeAnderson gut lattice, C. diff, FMT, SCFA, serotonin, colonization resistance
BiosignalPan-Tompkins ECG, HRV, SpO2, EDA, arrhythmia classification, multi-channel fusion
Drug DiscoveryMATRIX scoring, ADDRC HTS screening, iPSC validation pipeline
NLMESovereign FOCE/SAEM, NCA, diagnostic plots — replaces NONMEM/Monolix

Composes Into

ToadStool validation, NestGate (NCBI clinical data), biomeOS NUCLEUS (distributed health pipeline)

Referenced in 25 pages